Gabrielle Le Provost
Chargée de projet (post-doctorat) en biologie cellulaire cutanée , Université de
PhD in cell and molecular biology, I am currently working as a post-doctoral research associate on skin wound healing and scarring in Dr Christine Pullar’s group at the University of Leicester.
Working in several academic laboratories, as well as in collaboration with industrial partners, has allowed me to develop a range of technical and management skills including:
- extensive experience in cell and molecular biology (primary cell culture, development of transgenic stable cell lines, gene and protein expression, functional assays, histology)
- project management
- literature awareness
- experimental design and optimisation
- communication in internal and international meetings
- valorisation by publication of peer-reviewed articles
- laboratory management and student supervision
Please feel free to contact me if you are interested in my profile, or visit my online resume for more details: http://www.doyoubuzz.com/gabrielle-le-provost/p...
80 contactsResearch Associate in skin wound healing (post-doctoral fellowship) , Université de Leicester, Royaume Uni
Department of Cell Physiology and Pharmacology (Dr Christine Pullar)
Management of a research project focused on skin wound healing and scarring mechanisms
- Conception and experimental realisation, statistical analysis
- Protocol design and optimisation
- Laboratory management and student supervision
- Publication of a peer-reviewed article:
• β2AR antagonists and β2AR gene deletion both promote skin wound repair processes. Pullar CE, Le Provost GS, O’Leary AP, Evans S, Baier B and Isseroff R. Journal of Investigative Dermatology. in press
2006 - 2010PhD in Cell Biology an skin tissue engineering
Institute of Biology and Chemistry of Proteins, CNRS, Lyon. (Dr P.Sommer)
Management of a research project investigating regulation of epidermal differentiation and identification of new targets to improve renewal dynamics.
Collaboration with the company BASF-Beauty Care Solutions (dermo-cosmetics, Dr V.André)
Publications:
• Lysyl Oxidase silencing impairs keratinocyte differentiation in a reconstructed epidermis model.
Le Provost GS, Debret R, Cenizo V, Aimond G, Pez F, Kaniewski B, André V and Sommer P. Experimental Dermatology, 2010, 12: 1080-1087.
• The HIF-1-inducible Lysyl Oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth. Pez F, Dayan F, Durivault J, Kaniewski B, Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur J, Reynaud C. Cancer Research, 2011; 71(5): 1647-1657.
2005 - 2006Institute of Biology and Chemistry of Proteins. CNRS UMR 5086. Lyon. Supervisor: Dr P.Sommer
- Development a culture model to study keratinocyte differentiation and screen active ingredients. Collaboration with the company BASF-Beauty Care Solutions (dermo-cosmetics, Dr V.André)
2005 - 2005Laboratory « Human skin and Immunity », Edouard Herriot Hospital, Lyon. (Dr J. Péguet)
- Analysis of the phenotype of cutaneous dendritic cell precursors and their differentiated progeny
2004 - 2004Laboratory « Molecular biology of the cell », CNRS, Ecole Normale Supérieure de Lyon. (Dr P. Jurdic)
- Analysis of the trans-differentiation process between dendritic cells and osteoclasts and its implication in rhumatoid polyarthritis.
2003 - 2003Laboratory of Molecular Genetics (Dr H.Mittre)
- Development of a PCR procedure dedicated to the diagnosis of heterozygous deletions in the GNAS1 gene.